Wednesday, February 2, 2011

Testosterone Therapy

Many physicians in the past had generally administered one 200- 300 mg. dose of T every 21 days, but actually a 50 mg dose twice a week is more efficient therapeutically. Assuming all “other” systems are a go (which is to say, you have normal cholesterol, blood pressure, normal resting EKG and no signs of prostate problems), I, and many physicians, feel the best way to take testosterone, is via a cream, gel, or patch, with 50 to 100 mg per gram for men, and 1 to 6 milligrams per gram for women, if needed. The gel or cream can be compounded by a pharmacist with an absorption level approaching 15 to 30%. So the average absorption of 100 to 150 mg a week can be as effective as injection for many men. Ron Rothenberg MD, UC San Diego Professor, says that around half the men he sees for anti-aging use gel, or injection IM, and less than 10% use HCG to stimulate their own production of testosterone  and 5% use pellets (surgically implanted). I believe that a combination of these therapies will meet the most demanding man’s needs.
For example, creams yield more DHT which makes a man feel sexual and get erections with ease. The injections help to firm up the body with better muscle density and less estrogen conversion. The HCG tends to assist in the cosmetic issue of testicle size, because it increases the man’s own production of testosterone.
Testosterone used properly with knowledge of estrogen metabolism can actually improve prostate health. Studies are showing those with higher testosterone have lower rates of prostate cancer, those with higher estrogens have higher risk of prostate cancer. Testosterone can improve diabetes and strengthen arteries to reduce cholesterol and associated heart problems. The journal Neurology, implicates low testosterone levels in men with an increased risk of developing Alzheimer's disease. Another disadvantage of high dose testosterone injections (beside too much flux in steady T blood value), is that this practice, done too often, can increase the thickness of your blood (viscosity) because your hematocrit (measure of red blood cell count) and hemoglobin (the molecule that carries oxygen in the red blood cell) both increase.
"Synthetic Roids"
Reports are (believe it or not) some pro physique competitors are using upwards of 2,000-4,000 mg. of Testosterone every week.
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This is of course quite dangerous. Such an individual could hopefully decrease the risk from what could happen (stroke or heart attack),with a blood donation, once or twice a year. To further offset problems these men should work out very hard and do aerobics for coronary flow and eat very low Trans fat. They should not drink alcohol or smoke. Moreover, they are going to have enormous shrinkage of their own testes and an acutely and chronically depressed pituitary-testicle loop, such that, if and when they discontinue said dosages, it may be a very long time (if ever again), that they will produce normal counts of sperm, that have proper motility and viscosity, sufficient to be able to cause conception.
Now it should be noted that impotence is separate from sterility.
Impotency has been known to occur with the use of synthetic- Deca Durabolin, because it is chemically different than natural testosterone, and may leave chemicals in the body that are unnatural and counter productive to sexual function and good health. The oral steroid known as oxymethelone (one trade name is Anadrol-50), was developed specifically for Fanconi’s anemia. Colloquially, anemia is “iron-poor blood” due to low RBC count. Using Testosterone creams will negate increases in viscosity, since there’s rarely, any significant increase in RBC count. Overuse of synthetic testosterone (injected or some taken orally), or metabolically-produced excesses, can create excess estrogen in the male. In tissues sensitive to the process of estrogen conversion and deposition, it can manifest as localized and hardened fat deposits. One such condition is known gynecomastia. There are some drugs used to deal with this, but once the tissue significantly forms and hardens, surgery is the most likely solution.

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